Posts for tag: oral cancer

By Ray A Beddoe DMD, Pharm.D, M.S.
June 08, 2019
Category: Oral Health
Tags: oral cancer  
NewSalivaTestmayHelpIdentifyOralCancerEarlier

A half million people are diagnosed every year with oral cancer. While other cancers are more prevalent, oral cancer is among the most dangerous with only a fifty percent five-year survival rate.

A major reason for this low rate is because this fast growing cancer is difficult to detect early — diagnosis comes far too often after the disease has already well advanced. In an effort to detect cancer earlier many dentists visually screen for oral abnormalities during checkups, especially patients over fifty, tobacco or heavy alcohol users, patients with a family history of cancer or a medical history of exposure to the sexually transmitted human papilloma virus, HPV-16.

If they detect an abnormality, the dentist often refers the patient to an oral surgeon or other specialist for a possible biopsy. In this procedure the surgeon removes a sample of the abnormal tissue, which is then examined microscopically for cancer cells. A biopsy remains the most effective way to diagnose oral cancer.

Because of the disease's aggressive nature, many dentists lean to the side of caution when referring patients for biopsy. As a result 90% of oral biopsies reveal no cancer. Reducing the number of biopsy referrals is highly desirable, especially for the patient undergoing the procedure. Tissue samples tend to be large to ensure complete detection of any cancer cells. Depending on the size and location of the sample, there may be a risk for loss of function or disfigurement.

A new screening tool using a sample of a patient's saliva could help reduce the number of biopsy referrals. Besides DNA, saliva also contains dormant genes called biomarkers that activate in response to the presence of a specific disease. This particular saliva test identifies those biomarkers for oral cancer if they're present.

A sample with a low score of biomarkers indicates no cancer present (with a statistical confidence of 99%). A medium or high score indicates cancer may be present, but only a biopsy can determine for sure. Using this test, dentists might be able to reduce the number of biopsy referrals and instead be able to employ watchful waiting in certain cases. Because of its simplicity and non-invasiveness, saliva screening could help identify oral cancer earlier.

If you would like more information on early detection and treatment for oral cancer, please contact us or schedule an appointment for a consultation.

By Ray A Beddoe DMD, Pharm.D, M.S.
October 31, 2018
Category: Oral Health
Tags: oral cancer  
ReduceYourOralCancerRiskwithBetterDietandLifestyleChoices

You probably know practicing healthy dietary and lifestyle habits can help prevent tooth decay and periodontal (gum) disease. But good habits could also lower your risk for a more dangerous type of disease — oral cancer.

There are several risk factors for oral cancer, including those you can't do much about like your genetic makeup or unknown elements in the environment. But there are factors you can influence with your actions.

You're probably familiar with the links between tobacco use (both smoked and smokeless) and oral cancer. But excessive alcohol use could also increase your risk, as can risky sexual behavior that could expose you to human papilloma virus (HPV) 16.

And what you eat — or don't eat — could also influence your cancer risk. Research over the last half century has uncovered a link between diet and cancer. Cancer development seems to begin with damage to DNA, the genetic material that “tells” each of our cells what it is and what it does in the body. Substances called carcinogens found in the environment — including the foods we eat — can damage our DNA and open the door for cancer to development.

But some foods also contain elements that protect our DNA from carcinogenic damage. Some of these are known as antioxidants, which protect cells from unstable molecules called free radicals. You'll find antioxidants, as well as other protective substances like fiber, vitamins and lycopene in plant-based foods, particularly fruits and vegetables.

Eating a plant-based diet also means you'll eat fewer foods that contribute to the rise of free radicals like saturated fat, animal protein and nitrates (a chemical that occurs in some food processing). A healthy diet, along with quitting tobacco use and moderating alcohol consumption, will help not only preventing decay or gum disease, it will also drastically lower your risk for oral cancer.

If you would like more information on oral cancer prevention, please contact us or schedule an appointment for a consultation. You can also learn more about this topic by reading the Dear Doctor magazine article “Diet and Prevention of Oral Cancer.”

By Ray A Beddoe DMD, Pharm.D, M.S.
July 09, 2015
Category: Oral Health
Tags: nutrition   oral cancer  
AHealthyDietCouldLowerYourRiskofOralCancer

Good nutrition is vital for maintaining health and preventing disease, especially for your mouth. A diet rich in whole foods — fresh fruits and vegetables, protein and dairy products — and low in sugar will not only promote strong teeth and gums, but lessen your chances of developing tooth decay or periodontal (gum) disease.

Diet is also a prominent factor in reducing the risk for another serious mouth disease — oral cancer. While oral cancer makes up only 3% of total cancer cases reported annually, the five-year survival rate is a sobering 50%, much lower than for other types of common cancers. While genetics plays a role in your susceptibility to oral cancer, lifestyle choices and practices present the greater risk factors for the disease.

Of these lifestyle factors, refraining from tobacco products, moderating your alcohol consumption and avoiding risky sexual behavior are of primary importance in reducing your cancer risk. With that said, you should also take into account the foods that are part of your daily diet — both what you should and shouldn’t eat. As an example of the latter, some foods contain a class of chemicals known as nitrosamines that are carcinogenic (cancer-causing). One such chemical, nitrite, is used as a preservative in meats like bacon or ham, and may also be found in beer, and seafood products.

On the positive side, your diet should be rich in foods that supply antioxidants, substances that protect the body’s cells from damaging, unstable molecules known as free radicals. The best sources for antioxidants (more so than dietary supplements) are plant foods rich in fiber and vitamins C and E. Eating more of these may also reduce your intake of nitrates, animal fat and saturated fat.

Adopting a moderate, nutritious diet, along with exercise, can have a huge positive impact on your general health and quality of life. Along with other lifestyle changes, better dietary choices can also help ensure a healthy mouth and reduce your risk of oral cancer.

If you would like more information on the role of nutrition in reducing your risk of oral cancer, please contact us or schedule an appointment for a consultation. You can also learn more about this topic by reading the Dear Doctor magazine article “Diet and Prevention of Oral Cancer.”